ʻO ka Christianization o ka Yaquis ka mea i ʻae i ka mea haipule e hoʻolaha i 1609, a komo i ka panalāʻau o Sonora.
I ka wā o ke kolone, ua pili wale ʻo Sonora i nā pali o ka Sierra Madre Occidental ma waena o nā palena o ua mea lā. ʻO ka moku i holo ʻākau mai ka muliwai ʻo Yaqui, me Real de la Cieneguilla, i kapa ʻia ʻo Pimería Baja a me ka ʻaoʻao kūkulu ʻākau mai kēlā Real a hiki i ka muliwai ʻo Colorado - ma ka moku ʻĀkau o ʻAmelika ʻAmelika ʻĀkau - i kapa ʻia ʻo Pimería Alta.
ʻO ka moku ʻo Sonoran i kēia manawa kahi wahi liʻiliʻi ma ke komohana hema o ka mea i kapa ʻia ʻo Pimería, aia ma ka mokuʻāina ʻo Chihuahua a me Ostimuri, kahi ma ke kahakai o ke Kai Kūʻono ʻo Kaleponi, ma waena o nā kahawai ʻo Mayo a me Yaqui.
Ma 1614 nā mikionali ʻo Pérez de Rivas lāua ʻo Pedro Méndez Christianised the Mayans in the Ostimuri area, dividing the mission into three Districts: Santa Cruz (ma ka waha o Mayo), Navojoa a me Tesia.
Ua hoʻohui pū ʻia nā Tepahues me nā Cornicaris ma 1620. Ua hoʻokumu ʻo Makua Miguel Godínez i nā mikionali o San Andrés de Cornicari a me Asunción de Tepahui. . I kēlā makahiki nō i hoʻokumu ʻia ai ka Rectorate o San Ignacio, a i hui pū ʻia me nā mikiona ʻelima i haʻi mua ʻia, ʻo kēlā poʻe ʻo Bacúm, Torín a me Rahún, aia ma ka waha o ka Yaqui
Ma 1617 ua hoʻohuli ʻia ka Yaquis e nā mākua ʻo Pérez de Rivas lāua ʻo Tomás Basilio. Me ka ʻeha mau, nā haunaele, nā ʻeha a me nā pepehi kanaka, ua ʻoi aku ka wikiwiki a me ka hoʻohui ʻia o ka hoʻohuli ʻana o Sonora. Ma ka kenekulia 17 ua hoʻonui ka Jesuits a hoʻokumu i ka nuʻukia o Maycoba a me Yecora ma ke komohana hema o ka mea a lākou i ʻike ai ʻo Chínipas.
Ua hoʻokaʻawale ʻia nā mikiona mai ka muliwai ʻo Yaqui a hiki i ka ʻākau i ʻehā mau koleka: ʻo San Borja i hui ʻia i nā nuʻukia o: Cucumaripa a me Tecoripa. , hoʻokumu i ka 1619; Movas a me Onovas, i ka makahiki 1622; Sahuaripa i ka makahiki 1627; Matape i ka makahiki 1629; ʻO Onapa i ka makahiki 1677 a me Arivechi , i 1727. ʻO ka Rectorate o nā Kahu Hemolele ʻEkolu o Iapana i komo pū me Batuco i hoʻokumu ʻia ma 1627, ʻo Oposura i 1640 a me Bacadeguachi , ʻO Guazavas , ʻO Santa María Baceraca lāua ʻo San Miguel Bavispe , hoʻokumu ʻia i 1645. A ʻo ka Rectorate o San Javier i hoʻohui i nā mikioni o Ures i 1636; Aconchi, Opodepe a me Banámichi i ka makahiki 1639; ʻO Cucurpe lāua ʻo Arizpe i ka makahiki 1648, a ʻo Cuaquiárachi i ka makahiki 1655.
I ka makahiki 1687, ua komo ka mikionali ʻo Eusebio Francisco Kino i loko o ka Pimería Alta a ua hoʻomaka i nā mikionali o ka Rectorate o Nuestra Señora de los Dolores, ka hoʻokumu ʻana: Caborca, kahi a Francisco Javier Saeta i hoʻokau ʻia ai nāna e mālama i nā leka me kāna kākoʻo ʻuhane, Father Kino; Atil, Tubutama, Our Lady of Sorrows de Saric, Pitiquito, Aiil, Oquitoa, Magdalena, San Ignacio, Cocóspera and Imuris.
Ma hope o ka kipaku ʻia ʻana o ka Jesua, ua mālama ʻia nā mikionali ma luna o ka poʻe Franciscans, ka mea nāna i kūkulu hou ʻole a ua kaupalena ʻia lākou i ka hoʻāʻo ʻana e mālama i nā mea e noho nei. I ka manawa i hoʻokumu ai ka Jesuits i nā wahi noho ma Sinaloa a me Sonora, ua huli ka maka i ka panalāʻau o Kaleponi.
